Fluocinolone is a steroid that reduces inflammation or swelling. Tretinoin is a form of vitamin A that helps the skin to renew itself more quickly. Fluocinolone, hydroquinone, and tretinoin topical (for use on the skin) is a combination medicine used to treat melasma (dark skin patches) on the face. Fluocinolone, hydroquinone, and tretinoin topical may also be used for purposes not listed in this medication guide. You should not use fluocinolone, hydroquinone, and tretinoin topical if you are allergic to fluocinolone, hydroquinone, or tretinoin. To make sure this medicine is safe for you, tell your doctor if you have: Using fluocinolone, hydroquinone, and tretinoin topical during pregnancy could harm the unborn baby. Tell your doctor if you are pregnant or if you become pregnant while using this medicine. The pill form of tretinoin is known to cause birth defects. I’ve also provided my patients with numerous Retin A and/or HQ prescriptions over the years, helping them integrate it into their skin care treatments. If you can deal with a little dryness for a little while, you will reap the benefits. My patients are always looking for the best anti-aging trick out there. You simply cannot beat Vitamin A (Tretinoin, Retina A) along with Vitamin C Serum for anti-aging magic. If you have melasma and/or sun damage, our pharmacy can compound a little hydroquinone along with it, and you’re golden. Hydroquinone has been, and continues to be the gold standard in the treatment of melasma, brown patches on the face and other parts of the body that are exposed to the sun, and other skin discoloration due to its effectiveness and safety. Again, this combines with a little Vitamin A (Tretinoin, Retina A) and you’ve got a powerful cocktail for cell turnover and bright skin. 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