Tamoxifen drugs

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  1. neosd Well-Known Member

    Tamoxifen drugs


    Tamoxifen may cause cancer of the uterus (womb), strokes, and blood clots in the lungs. Tell your doctor if you have ever had a blood clot in the lungs or legs, a stroke, or a heart attack. Also tell your doctor if you smoke, if you have high blood pressure or diabetes, if your ability to move around during your waking hours is limited, or if you are taking anticoagulants ('blood thinners') such as warfarin (Coumadin). If you experience any of the following symptoms during or after your treatment, call your doctor immediately: abnormal vaginal bleeding; irregular menstrual periods; changes in vaginal discharge, especially if the discharge becomes bloody, brown, or rusty; pain or pressure in the pelvis (the stomach area below the belly button); leg swelling or tenderness; chest pain; shortness of breath; coughing up blood; sudden weakness, tingling, or numbness in your face, arm, or leg, especially on one side of your body; sudden confusion; difficulty speaking or understanding; sudden difficulty seeing in one or both eyes; sudden difficulty walking; dizziness; loss of balance or coordination; or sudden severe headache. You will need to have gynecological examinations (examinations of the female organs) regularly to find early signs of cancer of the uterus. If you are thinking about taking tamoxifen to reduce the chance that you will develop breast cancer, you should talk to your doctor about the risks and benefits of this treatment. You and your doctor will decide whether the possible benefit of tamoxifen treatment is worth the risks of taking the medication. If you need to take tamoxifen to treat breast cancer, the benefits of tamoxifen outweigh the risks. Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with tamoxifen and each time you refill your prescription. If you have been prescribed tamoxifen for breast cancer, you've likely heard that it can interact with some other medications. Since these interactions involve commonly used drugs and include over-the-counter and nutritional supplements, this is very important. In addition, you will likely be taking the medication for at least 5 to 10 years, making an awareness of possible interactions not just a momentary concern. It's been thought that there are some people who, due to genetic differences, may not benefit from the usual dose of the drug, but more recent research suggests these women do just as well with treatment. Tamoxifen is broken down into endoxifen by the cytochrome P450 enzyme CYP2D6. (There are also other enzymes such as CYP3A4 and others, but CYP2D6 is likely most significant). Anything that reduces the activity of this enzyme (CYP2D6) can result in a reduced amount of the active metabolite, and hence, less benefit. Reduced activity of the enzyme may occur if you are taking some other medications or if you have particular genetic variations that make the enzyme less active.

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    Tamoxifen prescription and dosage sizes information for physicians and healthcare professionals. Pharmacology, adverse reactions, warnings and side effects. Tamoxifen Nolvadex, a hormone therapy drug, is used to treat breast cancers and to. Tamoxifen attaches to the hormone receptor in the cancer cell, blocking. Jun 13, 2005. Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators SERMs, which have both estrogenic and antiestrogenic.

    Tamoxifen blocks the actions of estrogen, a female hormone. Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat some types of breast cancer in men and women. It is also used to lower a woman's chance of developing breast cancer if she has a high risk (such as a family history of breast cancer). Use a barrier form of birth control (such as a condom or diaphragm with spermicide) while you are using this medication and for at least 2 months after your treatment ends. Tamoxifen may also be used for purposes not listed in this medication guide. You should not use tamoxifen if you are allergic to it, or if you have a history of blood clots in your veins or your lungs, or if you are also taking a blood thinner such as warfarin (Coumadin). Before using this medicine, tell your doctor if you have liver disease, high triglycerides (a type of fat in the blood), a history of cataract, or a history of stroke or blood clot. Also tell your doctor if you if you are receiving chemotherapy or radiation treatment. side effect of tamoxifen is blood clots, including deep vein thrombosis (DVT) and pulmonary embolus. In some cases, health care professionals may use the trade name Nolvadex when referring to the generic drug name tamoxifen. This medication is classified as an "anti-estrogen." (For more detail, see "How this drug works" section below). You should seek emergency help and notify your health care provider immediately if you develop sudden chest pain and shortness of breath. Notify your health care provider within 24 hours if you notice that one leg is swollen, red, painful and/or warm to touch and the other is not. A side effect of tamoxifen can be the development of uterine cancer. Women who have not had a hysterectomy should have regular pap smears and gyn examinations. Abnormal vaginal bleeding should be reported to your health care provider.

    Tamoxifen drugs

    Tamoxifen Drug Interactions and Genetics - Verywell Health, Tamoxifen for Breast Cancer Treatment - Side Effects Susan G.

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  6. Ta MOKS i fen. Trade names Nolvadex®. uses generic names in all descriptions of drugs. Nolvadex is the trade name for tamoxifen. In some.

    • Tamoxifen - Chemotherapy Drugs - Chemocare.
    • DB00675 Tamoxifen - Tamoxifen - DrugBank.
    • Nolvadex tamoxifen Chemotherapy, Side Effects..

    Tamoxifen is used for the treatment of invasive breast cancer in men and women, the most common type of breast cancer, following surgery and/or radiation and for preventing invasive breast cancer in women at high risk for developing it. Oct 28, 2014. Tamoxifen is the generic form of the brand-name drug Soltamox, which is used to treat some types of breast cancer in men and women. Learn about Nolvadex Tamoxifen Citrate may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications.

     
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