Fluconazole vs ketoconazole

Discussion in 'International Pharmacy' started by promotion, 26-Aug-2019.

  1. Laserdo XenForo Moderator

    Fluconazole vs ketoconazole

    Background: Vaginal candidiasis (VC) is one of the most common fungal diseases. Candida albicans is the most common causative fungus and has been isolated from more than 80% of specimens obtained from women with VC. Ketoconazole is the first orally active antifungal, the dosage for VC is 200 mg twice daily for 5 days. Fluconazole is the newer oral antifungal, its dosage for VC is a single oral dose of 150 mg. Since fluconazole 150 mg is considerably expensive, a single dose of 100 mg ketoconazole and 40 mg fluconazole in combination has been tested for the treatment of VC. The results showed that from 11 women with confirmed VC, 1-2 weeks after drug administration, the mycological culture was negative in 8 women, positive in 1 woman, and 2 woman lost to follow-up. This promising result led to the present study with the objective to confirm the efficacy and safety of the above combination in a formal clinical trial. Nizoral (Ketoconazole) is a medication used on your skin to treat fungal infections; however, it takes several weeks for full recovery, and the directions are specific to each type of medication.

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    Ketoconazole and the newer agent fluconazole are both effective treatments for candida esophagitis in patients with AIDS. This multicenter. Fluconazole UK 49,858, a new orally administered bis-triazole, was compared with ketoconazole for activity in synthetic broth dilution susceptibility tests. CONCLUSIONS Fluconazole and ketoconazole demonstrated similar efficacy in the treatment of TV.

    При молочнице и других видах кандидоза применяется целый спектр препаратов. Из этого списка особо выделяют Клотримазол и Флуконазол, которые являются эффективными, популярными и доступными по цене противогрибковыми медикаментами. Чтобы понять, что лучше Клотримазол или Флуканазол надо познакомиться с каждым из этих препаратов по отдельности. К основным показаниям Клотримазола относят: Препараты местного назначения наносятся на инфицированные участки 2-3 раза в день на протяжении трех недель. Для профилактики рецидивов курс можно увеличить еще на две недели. Лекарственное средство в таблетированном виде принимают 1 раз в день по 1 таблетке на протяжении недели, специалисты рекомендуют делать это перед сном. Если положительный эффект не наступает, следует обратиться к врачу, чтобы подтвердить диагноз. Pityriasis versicolor is a superficial recurring mycotic infection frequently encountered in tropical countries. The challenge for clinicians is selecting an antifungal therapy that produces long-lasting cure, good patient compliance, and a low incidence of adverse effects. Three open-label, randomized, comparative multicenter studies were conducted in South America to assess the efficacy and safety of fluconazole (two 300-mg doses given 1 week apart, and, if necessary, a third dose given 1 week later) with those of ketoconazole (200 mg daily for 10 or 14 days), itraconazole (200 mg daily for 7 days), or clotrimazole 1% cream (two applications daily for 21 days) in the treatment of patients with mycologically proven pityriasis versicolor. Clinical signs and symptoms of skin infection and microscopic examination and cultures of lesion scrapings were assessed at baseline and on days 14, 30 (or 37 for patients who received the third fluconazole dose), and 60. Safety was assessed on days 7, 14, 30 (or 37 for patients who received the third fluconazole dose), and 60. A total of 388 patients received study drug: 194 in the three fluconazole groups and 194 in the ketoconazole, itraconazole, and clotrimazole comparator groups. The combined clinical response rate (cure plus improvement) at early follow-up (day 14) in the fluconazole treatment groups was 91.2%, a response that was maintained at the day 60 evaluation.

    Fluconazole vs ketoconazole

    Fluconazole versus ketoconazole in the treatment of oropharyngeal., Activity of fluconazole UK 49,858 and ketoconazole against Candida.

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  7. May 23, 2001. Ketoconazole is not recommended for toe onychomycosis given its potential. with griseofulvin, ketoconazole, itraconazole, terbinafine and fluconazole. Ointment Compared to Bifonazole-Urea Ointment for Removal of the.

    • Efficacy of Itraconazole, Terbinafine, Fluconazole, Griseofulvin and..
    • Fluconazole versus ketoconazole in the treatment of tinea.

    Low-dose ketoconazole-fluconazole combination versus fluconazole in single doses for the treatment of vaginal candidiasis. J Dermatolog Treat. 2002 Jun;13273-6. Fluconazole versus ketoconazole in the treatment of tinea versicolor. Farschian M1, Yaghoobi R, Samadi K. Whereas intravenous broad-spectrum antifungals such as fluconazole or lipid formulations of amphotericin B cover almost all. Ketoconazole topical, oral.

  8. fantomm Moderator

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